Ketosis may improve glycaemic control – can we use it in T2D therapy?

April 2018, Dr Chee L Khoo

Ketogenesis is the production of ketone bodies (KB) when glucose levels decline and the glucagon:insulin ratio is high. When the body is deprived of glucose, KB act as an alternative fuel source for brain, heart, kidneys and skeletal muscles. KB have also been shown to have other physiological functions including lower glucose levels.

To understand the potential therapeutic implications of KB, we need to revise our knowledge about KB metabolism.…