GP Voice

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Dasiglucagon – the new glucagon

February 2018, Dr Chee L Khoo

Hypoglycaemia is one of the most common endocrine emergencies and the most feared complication of having diabetes. Treatment of severe hypoglycaemia in patients who are unable to take oral treatment is limited to either glucagon or glucose injections both of which requires some experience in playing with syringes and bottles. Dasiglucagon, a novel soluble glucagon analog, is a ready to use rescue pen developed for treatment of severe hypoglycaemia.…

Diabetes and Oral Health – it cuts both ways!

Patients with diabetes commonly have significant dysfunction of the immune system leading to chronic inflammation in many organ systems. It is not uncommon to see patients with T2D suffering from oral and periodontal disease which has been shown to worsen the diabetes disease. What is less known but shown in many studies is that periodontal disease is associated with development of diabetes.  …

T2D – does it have to be progressive?

February 2018, Dr Chee L Khoo

It’s frustrating isn’t it when managing patients T2D. Patients adhere to diet and lifestyle the best they can, the HbA1c is “on target” but yet we have to keep layering more tablets or injections over time to maintain the constantly deteriorating glycaemic control. Can we do better than accepting without question the “progressive nature of T2D”?…

Saturated Fats – Good or Evil?

Unhealthy eating

October 2017 – Dr Chee L Khoo 

We have all been brought up to advise reducing total fat and saturated fatty acid intake, based on the presumption that replacing saturated fatty acids with carbohydrate and unsaturated fats will lower LDL cholesterol and should therefore reduce cardiovascular disease (CVD) events. Several meta-analyses of randomised trials and prospective cohort studies8–10 and ecological studies,2 largely done in European and North American countries showed either no association or a lower risk between saturated fatty acid consumption with total mortality and CVD events.…

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