Which risk factors in T2D increase infection risk?

27th April 2024, A/Prof Chee L Khoo

glucose variability

We know that suboptimal HbA1c increases the risk of micro and macrovascular complications in people with diabetes. We also know that suboptimal HbA1c increases infection risks in these people. There is increasing evidence that glucose variability is a potent predictor of complications. There are two ways to look at glucose variability – day to day variation as seen on continuous glucose monitoring and variability in HbA1c measured over years.…

NIA Diagnostic Imaging – Improved diagnosis for life

13th April 2024, NIA Diagnostic Imaging

At NIA Diagnostic Imaging, we are proudly the only Medical Imaging Provider in Southwest Sydney that has continued to Bulk-Bill ALL Medicare eligible examinations including:
• ALL Obstetric Ultrasounds
• ALL Interventional Procedures performed under Ultrasound or CT guidance
• Biopsy, FNA, Aspiration, Hook Wire Localisation, Pain Management Injections

At NIA Diagnostic Imaging we always aim to prioritise the health of our patients and are compassionate and diligent in our delivery of premium care.…

Lipid lowering in T2D – what happens if you don’t treat to guidelines?

28th March 2024, A/Prof Chee L Khoo

We all know that high LDL-C is absolutely and adversely associated with cardiovascular mortality and morbidity. It’s been “proven” again and again in large clinical trials and meta-analyses after meta-analyses. Reducing lipids levels have also been shown to reduce cardiovascular (CV) events in secondary as well as in primary prevention. This is particularly the case in those with intermediate to high CV risks.…

Young T2D – do they get more cancers?

28th March 2024, A/Prof Chee L Khoo

Young T2D

We all know that when type 2 diabetes (T2D) presents at a younger age, they tend to be more aggressive in its progression as well as in the complications it causes. The complications also emerge earlier as well more aggressive. There are more cardiovascular events, more renal events and now, increasingly recognised, more liver complications.…

Lean body mass loss – can we prevent it?

7th March 2024, A/Prof Chee L Khoo

Total body weight loss

There was some kerfuffle recently in the lay press about muscle loss with semaglutide. Great horror? Well, it doesn’t matter how you lose the weight. Any significant body weight loss will incur lean body mass loss (LBM). It’s not unique to GLP1-RA injections. Weight loss from bariatric surgery, dietary restrictions or just healthier eating will do the same.…

BP control – a novel way to address medication adherence?

24th February 2024, A/Prof Chee L Khoo

BP Control

We all know how important it is for BP control in prevention cardiovascular, cerebrovascular and renal complications. We are also aware of the difficulty is improving medication adherence. We have a broad range of effective BP lowering medications covering diverse classes of medications. Anti-hypertensives work only if our patients take them regularly.…

Patients with high lipoprotein a – should they be on aspirin?

24th February 2024, A/Prof Chee L Khoo

Primary CVD prevention

In May 2022, the US Preventative Services Task Force (USPSTF) recommended that we avoid routine aspirin for primary prevention of CVD for anyone at all (1). In particular, for those between 40–59-year-old with a 10-year CVD risk 10%, the decision to initiate aspirin for the primary prevention should be an individual one as the evidence of the net benefit of aspirin use in this group is small.…

Uterine artery doppler – when would you order one?

13th February 2024, NIA Diagnostic Imaging

Uterine Artery

Commonly, uterine artery doppler ultrasound is conducted to measure the blood flow in the uterine arteries. This specific ultrasound allows for qualitative information to be gathered on the presence/absence of flow, the direction of flow, the quality of flow, to determine if the flow is laminar or turbulent and to distinguish waveform shape (low resistance, high resistance, early diastolic notch) (Naguib et al.,2012).…

T2D remission: can it happen in real world in primary care?

11th February 2024, A/Prof Chee L Khoo

Significant weight loss of >10% body weight has been associated with remission of type 2 diabetes. It’s not surprising, really, is it? The DiRECT trial which reported in 2018 demonstrated that early in T2D, significant weight loss can lead to remission of T2D (1). Importantly, DiRECT showed that weight loss of >10% can be achieved in primary with minimal support.…

Hypertriglyceridaemia – the forgotten villain?

11th February 2024, A/Prof Chee L Khoo

hypertriglyceridaemia

Hypertriglyceridaemia (HTG) often accompanies hypercholesterolaemia but that is often ignored as it is considered to be a minor villain. Older clinical trials on lipid lowering agents excluded subjects with HTG and that is partly why the significance of HTG is often ignored. The interplay between HTG and atherosclerotic cardiovascular disease (ASCVD) is real but extremely complicated.…

Salpingectomy to prevent ovarian cancer?

27th January 2024, A/Prof Chee L Khoo

Ovaries

The World Health Organisation classifies epithelial ovarian carcinomas into several morphological categories according to cell type: serous carcinomas (SC), mucinous carcinomas, endometrioid carcinomas, and clear-cell carcinomas, transitional-cell Brenner tumours, mixed, and undifferentiated type [1]. SC account for 75-80% of epithelial carcinomas and are subdivided into high-grade SC (HGSC) and low-grade SC (LGSC). Like any other cancers, early diagnosis would be important to improve the prognosis but often when diagnosed, ovarian cancer is in its advanced stages.…