26th August 2021, Dr Chee L Khoo
The Delta variant, first identified in India in December 2020, spread rapidly throughout a mostly unvaccinated country and caused massive numbers of cases, hospitalisations, and deaths. It’s now responsible for the outbreaks spreading across the world. This includes countries that have high vaccination rates. In the UK, the Delta variant has spread rapidly.…
21st August 2021, Dr Chee L Khoo
Nothing scares patients with diabetes more than blindness. Although we have many treatment options available for proliferative diabetic retinopathy and macular oedema, diabetes remains the leading cause of severe visual impairment in working-aged adults. Diabetic retinopathy affects one in three people with diabetes. Risk factor control and screening are the cornerstones for retinopathy prevention.…
18th August 2021, Spectrum Medical Imaging
We were all taught that we should always see it for ourselves and trust no one when it comes to history and examination. We cannot rely on third party information but sometimes, we have to. When we have to refer patient for imaging, we need to ensure that we can trust the provider and have faith in their experience and quality of reporting.…
14th August 2021, Dr Chee L Khoo
Shoulder pain has to be one of the most common musculoskeletal complaints in general practice. Rotator cuff pathology makes up at least 70% of those cases (1). It is commonly very debilitating, causing pain the whole night, causing significant reduction in function and often last for years. Apart from rest, analgesia, non-steroidal anti-inflammatory drugs, treatment options include physiotherapy, corticosteroid injections and surgical repair.…
8th August 2021, Dr Chee L Khoo
We know that the incidence of thrombocytopaenic thrombosis syndrome (TTS) can occur with the AstraZeneca (AZ) Covid-19 vaccines although it is pretty uncommon. What do you do with patients who had TTS with the first jab and it’s now ready for the next jab? Obviously, they can’t have the second jab with AZ.…
7th August 2021, Dr Chee L Khoo
It is always difficult for pregnant women to decide whether to have the Covid-19 vaccine during pregnancy. Understandably, they are concerned about the safety of the vaccine administered during pregnancy. When the pandemic started last year, there were some studies which suggest that Covid-19 during pregnancy is associated with “significantly” poor maternal and offspring outcomes.…
28th July 2021, Dr Chee L Khoo
Muscular strains especially those around the spine (low back or neck pain) are very common presentations in general practice. Apart from analgesics, muscle relaxants are commonly prescribed. Recommendations for the use of muscle relaxants have, however, conflicted between international clinical practice guidelines for low back pain (1,2). The US guideline recommends non-benzodiazepine antispasmodics as the drug of choice for acute low back pain (3) the Belgian guideline discourages such use (4) and the UK guideline does not make a recommendation (5).…
23rd July 2021, Dr Chee L Khoo
It’s all too confusing. And annoying. They keep releasing updates in the lay media and says “see your GP to discuss” but did not update us. You will recall that 2 weeks ago the recommendations to have the second AstraZeneca vaccination moved to 6 weeks after the first vaccination in areas with the outbreak which is pretty much all of Sydney.…
14th July 2021, Dr Chee L Khoo
The risk for people in the general population of developing type 1 diabetes (T1D) is about 1 in 300. For those who have a family member with T1D, the risk is 1 in 20. T1D progresses over 3 stages. In stage 1, two or more autoantibodies are already slowly attacking the β-cells. This can occur years before clinical diagnosis of T1D.…
11th July 2021, Dr Chee L Khoo
3 years ago we previewed the highly anticipated drug LY3298176, a novel dual GLP1 and GIP receptor agonist which activate both GLP1 and GIP receptors in islet cells when we look at twincretins. In healthy human subjects, LY3298176 caused weight loss and improved glucose tolerance. In subjects with T2D, LY3298176 reduced fasting glucose, glucose excursions and body weight with increasing doses.…
10th July 2021, Dr Chee L Khoo
In medical school, we were taught that the cerebral spinal fluid (CSF) provides the brain with nutrients, transports catabolites and the blood brain barrier (BBB) keeps nasties out and maintains a stable environment (homeostasis). Now, keeping nasties out is great but how does the brain get rid of the waste it generates?In the last fortnight, we explored how the brain cleans itself of toxic and waste products.…
27th June 2021, Dr Chee L Khoo
We all do it. Either we arrange for patients to come in once a year to have a “general check-up” or patients come in requesting one. There are no set rules what we check for and what blood tests to order. Somehow, patients feel better that they have been given a clean bill of health and at times, we feel that we have check them out properly and all is good.…