Stroke prevention – are two agents better than one?

13th December 2020, Dr Chee L Khoo

Stroke prevention

If you have been following GPVoice over the years, you would have realised that I am easily confused. I am confused again. Why are some patients who has had a TIA or minor stroke on aspirin and some on dual antiplatelet therapy (DAPT)? With supplies of some of these agents interrupted during the pandemic, can we swab one anti-platelet agent for another?…

Taking the hassles out of workers comp referrals

28th November 2020, Spectrum Radiology

paperwork galore

Don’t we hate it? Paperwork, approvals, waiting for more forms, more tick boxes, scan and fax and more waiting. That is what happens frequently with workers comp cases when patients need more investigations. What if you can get someone else to do it? Someone else other than you practice staff.

You now have a choice.…

Covid-19 vaccines – what are the issues?

27th November 2020, Dr Chee L Khoo

Covid-19 vaccine

Coronaviruses compose a family within the Nidovirales order and replicate by use of a nested set of mRNAs. Four seasonal human coronaviruses (229E, NL63, OC43, and HKU1) have been identified as causing up to a third of community-acquired upper respiratory tract infections. Yet our knowledge about the immune response against this family of viruses is very limited.…

Pro-opio-melanocortin deficiency obesity – what has it taught us?

obese kids?

27th November 2020, Dr Chee L Khoo

Every so often you come across reports of some “ultra-rare” disease that has a treatment available now and you probably thought that it really doesn’t concern you or your patients. In a recent small study reported in The Lancet, Karine Clément, Erica van den Akker et. al. presented the results of setmelanotide in participants with proopio-melanocortin (POMC) gene mutation which is associated with severe childhood obesity.…

Does wearing a facemask cause hypoxia?

14th November 2020, Dr Chee L Khoo

facemasks

It’s been at least 12 weeks since we started to wear facemasks at the practice full time with all face to face consultations. I must admit that during the first week, I did feel a bit suffocating with the mask on. I remember having to stop mid-sentence to catch my breath. I could sympathise with many patients, particularly patients who has COPD, asthma or heart failure.…

Covid-19 and newborn – scary stuff?

25th October 2020, Dr Chee L Khoo

Covid-19 and newborn

Although our numbers of new Covid-19 infections and community transmission is pretty good in comparison with most other countries in the world, it isn’t zero. This is as good as it gets for at least the next 12 months. One of the scariest things is transmission of the virus to the newborn if the pregnant mother has the Covid-19 infection.…

Aortic aneurysm and fluoroquinolones don’t mix well – do they?

13th October 2020, Dr Chee L Khoo

Aortic aneurysm (AA) and aortic dissection (AD) are potentially fatal conditions. Without treatment, ruptured AA/AD carries a mortality rate of up to 90%. Population-based studies estimated the annual incidence to be 2.4 to 14.8 per 100 000 persons for AA (1-4) and 3.8 to 8.8 per 100 000 persons for AD (3,5-7). Although the incidence varied across countries, the number has universally increased over time (1-5,7).…

Can lifestyle measures prevent GDM?

12th October 2020, Dr Chee L Khoo

We know from various diabetes prevention programs that intensive lifestyle interventions can be successful in reducing progression to diabetes. As GDM is more common in women with higher BMI and in the many high- risk groups and it is logical to ask the question “can we prevent GDM in these women?” If we could reduce progression of patients who has prediabetes to diabetes, we should, in theory, reduce prevalence of GDM in women who are at high risk of GDM.…

Temporal arteritis – which features help with the diagnosis?

11th October 2020, Dr Chee L Khoo

There are a few “rare” medical diagnoses that are stuck in our minds since medical school days. They may be rare but it’s important not to miss them. Temporal arteritis, also known as giant cell arteritis (GCA) is one of those not so common conditions. It is actually not that rare. It is the most frequent primary systemic vasculitis with an annual incidence rate of 15–25 per 100,000 in Caucasians ≥50 years of age and it primarily affects medium- and large-sized vessels (1,2).  When do you suspect GCA?…

If your patient need interventional procedures, go to an expert

interventional procedures

29th September 2020, Spectrum Medical Imaging

Do your patients need Interventional procedures performed?
Interventional Radiology provides patients with access to a vast array of treatment options that do not require surgery. This is a rapidly expanding speciality which grows with every incremental advance in medical imaging technology. Spectrum provides Interventional Radiology services across Sydney in both Private and Public settings.…

Hypoglycaemia in non-diabetics – is it a problem?

hypoglycaemia

27th September 2020, Dr Chee L Khoo

We know that hyperglycaemia is associated with increased cardiovascular mortality. We also know that in patients with diabetes, hypoglycaemia is also associated with increased cardiovascular morbidity and mortality. What about patients who don’t have diabetes and have low blood glucose (<4.0 mmol/L)? I am sure we all have patients who do not have diabetes but on screening blood tests, have BSL lower than 4.0 mmol/L.…