Incretin therapy for CV benefits – here comes the agents
28th December 2025, A/Prof Chee L Khoo We discussed the Lancet Commission’s clinical obesity 12 months ago. Clinical obesity is obesity in the presence of a clinical disease (whether complication or co-morbidity). This is why the PBS is funding semaglutide for patients with obesity and established cardiovascular (CV) disease and not obesity on its own. […]
AF in athletes – the reverse J-curve
25th December, 2025, A/Prof Chee L Khoo With increasing prevalence of obesity, type 2 diabetes, hypertension and obstructive sleep apnoea, we are encountering increasing prevalence of atrial fibrillation in our practice. These are the common risk factors which we associate with a higher risk of developing AF. Surprisingly, there is one group which stands out […]
Should we screen for helicobacter infection in patients on aspirin?
29th September 2025, A/Prof Chee L Khoo I must admit that I have been doing this for many years on an ad hoc basis. I have been screening for helicobacter pylori (HP) infection in patients who need to be on aspirin (primary or secondary prevention of coronary artery disease). This isn’t what is recommended in […]
Fitness and colorectal cancer – is there a connection?
23rd August 2025, A/Prof Chee L Khoo Not very often do you come across two significant studies on the same topic within weeks of each other. Over the last two months, two very interesting trials reported on the influence of exercise and fitness on risk of colorectal cancer (CRC) and the risk of recurrence of […]
What happens if you become frail?
14th July 2025, A/Prof Chee L Khoo It’s amazing how we have learnt to accept declining muscle function and increasing frailty as part of our patients getting older. At GPVoice, we have explored muscle health and sarcopenia many times over the couple of years. We know that declining muscle health is associated not only with […]
The new ADIPS recommendations for GDM – how did we get here?
30th June 2025, A/Prof Chee L Khoo You would have no doubt noticed headlines everywhere about the new criteria for GDM diagnosis that was just released a few days ago. Why is there such a buzz? Why is everyone seemingly that excited? We have covered many of the issues covered by ADIPS over the years […]
Who should not go vegan?
30th June 2025, A/Prof Chee L Khoo There are many reasons why some of our patients go vegetarian. A primarily plant-based diet with less meat is supposed to lower the morbidity of chronic diseases, including cardiovascular diseases, type 2 diabetes, and certain cancers [1]. Some patients may choose to reduce their food-related ecological footprint. A […]
Atrial fibrillation – paradigm changes in management
11th June 2025, A/Prof Chee L Khoo Atrial fibrillation (AF) is associated with 1.5 – 2-X risk of death (1,2), 2.4-X risk of stroke (2), 5-X risk of heart failure (HF) (2), 1.5-X risk of myocardial infarction (MI) (3), 2-X risk of sudden cardiac death (4), 1.6-X risk of chronic kidney disease (CKD) (2), 1.5-X risk of cognitive impairment […]
New Acute Coronary Syndrome guidelines – is it relevant to GPs?
24th May 2025, A/Prof Chee L Khoo One of the problems keeping up to date in primary care is not being aware of new guidelines that has been released. Well, the joint National Heart Foundation and Cardiac Society of ANZ released the new Australian clinical guideline for diagnosing and managing acute coronary syndromes (ACS) just […]
Understanding coronary artery calcium (CAC) scoring
14th May 2025, NIA Diagnostic Imaging Coronary artery calcium (CAC) scoring is a well-established, non-invasive imaging technique for assessing cardiovascular risk by identifying and quantifying calcified plaque in the coronary arteries. The CAC score, a direct marker of subclinical atherosclerosis, highly predicts future cardiovascular events, making it an essential tool for clinicians in assessing risk, […]
Prescribing exercise in T2D – when is a good time?
13th April 2025, A/Prof Chee L Khoo Continuous glucose monitoring (CGM) was first shown to be beneficial in the management of patients with type 1 diabetes. Later on, patients with type 2 diabetes on insulin also found CGM beneficial in more ways than one. Of course, patients with T2D not on insulin also found CGM […]
Do anti-depressants hasten cognitive decline in dementia?
28th February 2025, A/Prof Chee L Khoo Every so often you come across a study where the initial and immediate impression is that there must be more to the conclusion. The latest study which connects the use of anti-depressants with further cognitive decline in patients with dementia is just one of those studies. Now, many […]