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Diabetes & Obesity

How to create a weight loss program for patients with T2D

13th May 2019, Dr Chee L Khoo Type 2 diabetes is strongly associated with obesity and abnormal fat distribution. Fat loss especially from the liver and pancreas have been shown to reduce insulin resistance and, in some cases, lead to diabetes remission. Bariatric surgery can…

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The young T2D – more trouble ahead than you think

13th May 2019, Dr Chee L Khoo You are already seeing the worrying trend of younger and younger patients being diagnosed with type 2 diabetes (T2D). My youngest is 25 years old when first diagnosed with T2D. I am sure many of you have patients…

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Ramadan is here – do we need to do anything different with patients with diabetes?

13th May 2019, Dr Chee L Khoo Ramadan is the holy month for Muslims, falling in the ninth lunar month in the Islamic calendar year. Because the timing of Ramadan is linked to the sighting of the new moon, the timing of this month varies….

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Diabetes inducing drugs – who is next on the list?

13th May 2019, Dr Chee L Khoo The list of drugs that increase the risk of type 2 diabetes (T2D) is increasing. We know statins (1,2), anti-psychotics (3) and many of the anti-retroviral (4) and immunosuppressant agents (5) have been shown to increase the risk…

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Breakfast – how important is it?

23rd April, 2019, Dr Chee L Khoo Somehow, it has been drummed into us, as doctors and consumers, that breakfast is the most important meal of the day. What does that even mean? As discerning scientists, we should seek to clarify what outcome measures they…

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Weight loss with Duromine® – how safe is Duromine®?

14th April 2019, Dr Chee L Khoo It’s difficult, isn’t it? Patients who are overweight or obese often has either significant cardiovascular risks or already have cardiovascular co-morbidities. These are the patients that need some assistance with weight loss but we always hesitate to prescribe…

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Reduction of major CV events by SGLT2 inhibitors – who will benefit from what?

13th April 2019, Dr Chee L Khoo SGLT2 inhibitors, as a class of anti-diabetic drugs, have been shown in multiple cardiovascular outcomes trials (EMPA-REQ, DECLARE-TIMI 58, CANVAS) to “reduce cardiovascular events in patients with type 2 diabetes (T2D)”. These are big headlines but as obsessive…

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Low birth weight and future cardiovascular risk – how are they connected?

13th April 2019, Dr Chee L Khoo We know that overweight children have higher future risk of cardiovascular disease and diabetes.  Ironically, babies who are small at birth or during infancy also have increased rates of cardiovascular disease and diabetes as adults. It is thought…

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Continuous glucose monitoring – how accurate are they?

13th April 2019, Dr Chee L Khoo The monitoring of plasma glucose levels is crucial when we are titrating insulin doses, correlating lifestyle messages with glucose control and in detecting asymptomatic hypoglycaemia. Until now, finger-prick glucose checking is the gold standard for self-monitored blood glucose…

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Fournier’s gangrene & SGLT2i – how rare is it?

23rd March 2019, Dr Chee L Khoo You may remember receiving warnings recently from the Therapeutics Goods Administration (TGA) about a serious “rare” infection, called necrotising fasciitis of the perineum, also referred to as Fournier’s gangrene (FG). FG is reported to be associated with the…

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Maintaining weight loss in primary care – is it possible?

23rd March 2018, Dr Chee L Khoo The DiRECT trial is really a landmark study which shows that remission of type 2 diabetes (T2D) is possible with weight loss and more importantly, it can be achieved in primary care. The result from DiRECT was most…

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Insulin-GLP1 agonist combo – two heads better than one

23rd March 2019, Dr Chee L Khoo American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD) suggest that if HbA1c targets are not achieved despite the addition of basal insulin in type 2 diabetes (T2D), treatment could also be further…

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